Identification and validation of a necroptosis-related gene prognostic signature for colon adenocarcinoma
نویسندگان
چکیده
Background: Necroptosis is a novel programmed cell death pathway proposed in 2005, which mainly activated by the tumor necrosis factor (TNF) family and mediates cellular disassembly via receptor interacting serine/threonine kinase 1 (RIPK1), 3 (RIPK3) mixed lineage domain like pseudokinase (MLKL). We tried to analyze relationship of necroptosis-related genes (NRGs) expression with colon adenocarcinoma (COAD) propose potential therapeutic targets through immunological analysis.
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ژورنال
عنوان ژورنال: Translational cancer research
سال: 2023
ISSN: ['2218-676X', '2219-6803']
DOI: https://doi.org/10.21037/tcr-23-494